QuickView for FAS receptor;jsessionid=35D9D7F1A4F66F241A47224570DFEE9A;jsessionid=40CAB5D494EEBC5F03C4675D9C191DD1 (gene)
- Gene Symbol:
- Fas
Mus musculus - Full name:
- Fas (TNF receptor superfamily member 6)
- Synonyms:
- AI196731, APO1, APT1, CD95, TNFR6, Tnfrsf6, lpr, tumor necrosis factor receptor superfamily member 6, FASLG receptor, Fas (TNF receptor superfamily member), Fas antigen, apo-1 antigen, apoptosis-mediating surface antigen FAS, lymphoproliferation
- Genomic Location:
- Chr 19: 34365156-34402260
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Bos taurus , Gallus gallus , Canis lupus familiaris , Pan troglodytes , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
kinase binding | transmembrane signaling receptor activity | enzyme binding | protein-containing complex binding | death receptor activity | signaling receptor activity | identical protein binding | protein binding | tumor necrosis factor-activated receptor activity | protease binding | calmodulin binding
GO Biological Process
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | leukocyte homeostasis | negative regulation of leukocyte activation | response to extracellular stimulus | cellular response to increased oxygen levels | protein homooligomerization | adaptive immune response | regulation of extrinsic apoptotic signaling pathway in absence of ligand | regulation of cysteine-type endopeptidase activity | response to nutrient levels | negative regulation of immune system process | response to cytokine | positive regulation of cellular component organization | regulation of B cell activation | motor neuron apoptotic process | positive regulation of apoptotic process | regulation of programmed cell death | necroptotic process | epithelial cell apoptotic process | regulation of immune system process | response to hormone | cellular response to hyperoxia | neuron death | negative regulation of cellular process | dendrite regeneration | response to metal ion | cellular response to tumor necrosis factor | cell differentiation | nervous system development | cellular response to extracellular stimulus | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | neurogenesis | positive regulation of phosphate metabolic process | regulation of protein oligomerization | regulation of organelle organization | generation of neurons | negative T cell selection | regulation of neuron death | necroptotic signaling pathway | cellular process | lymphocyte differentiation | extrinsic apoptotic signaling pathway | neuron development | programmed necrotic cell death | immune system development | negative regulation of apoptotic process | positive regulation of release of cytochrome c from mitochondria | cellular response to starvation | regulation of proteolysis | positive regulation of catalytic activity | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | response to inorganic substance | regulation of cell differentiation | regulation of lymphocyte apoptotic process | regeneration | regulation of cellular process | leukocyte activation | regulation of apoptotic process | regulation of metabolic process | regulation of protein complex assembly | positive regulation of cellular protein metabolic process | negative thymic T cell selection | cellular component organization | cellular response to metal ion | T cell activation | inflammatory cell apoptotic process | response to stimulus | cellular response to lithium ion | positive regulation of protein metabolic process | positive regulation of peptidase activity | response to stress | negative regulation of lymphocyte activation | regulation of cell proliferation | positive regulation of cysteine-type endopeptidase activity | circadian rhythm | response to starvation | programmed cell death | cellular response to inorganic substance | Fas signaling pathway | rhythmic process | positive regulation of proteolysis | extrinsic apoptotic signaling pathway via death domain receptors | hemopoiesis | cellular component assembly | positive regulation of mitochondrion organization | regulation of lymphocyte differentiation | leukocyte differentiation | regulation of cellular response to stress | apoptotic process | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | system development | cellular response to nutrient levels | response to oxygen levels | regulation of signal transduction | positive regulation of organelle organization | multicellular organism development | regulation of peptidase activity | regulation of MAPK cascade | protein complex oligomerization | leukocyte mediated immunity | spleen development | regulation of catalytic activity | regulation of phosphorylation | cellular response to amino acid starvation | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | cellular response to stress | response to lipid | death receptor activity | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of lymphocyte activation | cellular response to oxygen levels | regulation of nitrogen compound metabolic process | neuron apoptotic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | cytokine-mediated signaling pathway | positive regulation of protein complex assembly | response to corticosteroid | response to lithium ion | positive regulation of hydrolase activity | homeostasis of number of cells | T cell apoptotic process | cellular response to cytokine stimulus | neuron projection regeneration | regulation of cellular protein metabolic process | response to hyperoxia | hepatocyte apoptotic process | positive regulation of endopeptidase activity | positive regulation of neuron death | response to toxic substance | positive regulation of leukocyte apoptotic process | regulation of apoptotic signaling pathway | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | regulation of mitochondrion organization | positive regulation of extrinsic apoptotic signaling pathway | cell communication | regulation of cellular metabolic process | regulation of neuron apoptotic process | lymphocyte homeostasis | negative regulation of cell activation | regulation of protein metabolic process | positive regulation of signal transduction | homeostatic process | regulation of protein phosphorylation | apoptotic signaling pathway | negative regulation of B cell activation | activation-induced cell death of T cells | lymphocyte activation | positive regulation of molecular function | neuron differentiation | T cell differentiation | protein-containing complex assembly | regulation of protein homooligomerization | positive regulation of protein modification process | T cell selection | response to organic substance | T cell differentiation in thymus | regulation of hemopoiesis | regulation of intracellular signal transduction | positive regulation of neuron apoptotic process | anatomical structure development | cell surface receptor signaling pathway | cell projection organization | metabolic process | immunoglobulin production | negative regulation of programmed cell death | positive regulation of cell death | immune response | neuron projection development | thymic T cell selection | positive regulation of cellular component biogenesis | organic substance metabolic process | cell death | tumor necrosis factor-activated receptor activity | animal organ development | gene expression | regulation of cell activation | positive regulation of programmed cell death | tumor necrosis factor-mediated signaling pathway | regulation of phosphate metabolic process | renal system process | T cell homeostasis | cell activation | positive regulation of lymphocyte apoptotic process | regulation of stress-activated MAPK cascade | regulation of cell communication | signaling | response to organic cyclic compound | cell development | positive regulation of protein homooligomerization | extrinsic apoptotic signaling pathway in absence of ligand | positive regulation of phosphorylation | regulation of endopeptidase activity | dendrite development | regulation of developmental process | B cell mediated immunity | developmental process | positive regulation of protein oligomerization | necrotic cell death | response to amino acid starvation | positive regulation of metabolic process | immune system process | hematopoietic or lymphoid organ development | response to tumor necrosis factor | cellular response to organic substance | regulation of cell death | response to steroid hormone | negative regulation of cell death | regulation of cellular component organization | positive regulation of apoptotic signaling pathway | positive regulation of signaling | signal transduction | regulation of signaling | response to glucocorticoid | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
secretory granule | integral component of membrane | dendrite | intracellular membrane-bounded organelle | sarcolemma | apical plasma membrane | neuron projection | somatodendritic compartment | cytoplasmic vesicle | cell body | cell | nuclear lumen | neuronal cell body | plasma membrane protein complex | intrinsic component of membrane | external side of plasma membrane | cytoplasm | death-inducing signaling complex | intracellular organelle | membrane microdomain | nuclear body | dendritic tree | apical part of cell | protein-containing complex | cell projection | secretory vesicle | endomembrane system | CD95 death-inducing signaling complex | nucleoplasm | plasma membrane | membrane raft | vesicle | perinuclear region of cytoplasm | extracellular region | membrane-bounded organelle | nucleus | organelle | extracellular space | apical dendrite | cell periphery | membrane-enclosed lumen | cytosol | intracellular vesicle | cell surface | intracellular | membrane
